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| Preface6 1 Lifeenergy and metabolism 2 Energyentropy and the universe 3 Energyentropy and the living cell 4 Gibbs free energy--measurement and applications 5 Chemical and electrochemical potential 6 Oxidation/reduction (redox) potentials 7 ATP and ion gradients: 'intermediate' energy stores 8 Substrate level phosphorylations 9 Free oxygen: its benefits and dangers 10 Cofactors in oxidation/reduction reactions 11 The mitochondrial respiratory chain: 1 Path of electron flow 12 The mitochondrial respiratory chain: 2 Organization of peptides 13 Electron transfer mechanisms 14 Respiratory chains in bacteria 15 Photosynthesis in green plants: 1 Path of electrons 16 Photosynthesis in green plants: 2 Structure of the reaction centre 17 Photosynthesis in green plants: 3 Organization of membranes 18 Photosynthesis in bacteria 19 Energy transduction 20 Energy transfer via a H + gradient--testing the model 21 Stoichiometries in ATP synthesis 22 Measurement of the H +/P ratio: 1 Kinetic approaches 23 Measurement of the H +/P ratio: 2 Thermodynamic approaches 24 Generation of a proton gradient: 1 Mechanisms involving organic hydrogen carriers 25 Generation of a proton gradient: 2 'Direct' proton pumping 26 The ATP synthase complex 27 F1--structure and function relationships 28 Mechanism of ATP synthesis: 1 Energetics 29 Mechanism of ATP synthesis: 2 Enzyme mechanism 30 Fo--structure and function relationships 31 Integration ofmitochondria and cytoplasm 32 Control of ATP synthesis: l Thermodynamic aspects 33 Control of ATP synthesis: 2 Kinetic aspects -. 34 Uncoupling electron transfer from phosphorylation 35 Human mitochondrial defects and disease 36 Integration of chloroplast and cytoplasm 37 Alternative uses of the proton gradient: 1 Heat generation 38 Alternative uses of the proton gradient: 2 Transport systems 39 Alternative uses of the proton gradient: 3 Bacterial motion 40 Alternative methods of gradient generation: 1 Bacteriorhodopsin 41 Alternative methods of gradient generation: 2 Primary sodium pumps 42 ATP-driven ion pumps: an overview 43 P-type ATPases: 1 Structural aspects 44 P-type ATPases: 2 Energetic aspects 45 Evolution ofbioenergetic systems Reading list Index |
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