最 低 价：￥1042.50
定 价：￥1767.00
作 者：Ram I. Mahato 著 著
出 版 社：Oversea Publishing House
出版时间：2002-6-1
I S B N：9780415283854
| Ram Mahato is at the University of Tennessee in Memphis, USA and Sung Wan Kim is at the University of Utah, USA.
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| List of color plates List of figures List of tables List of contributors Foreword Preface 1 Basic components of gene expression plasmids 2 Inducible gene expression strategies in gene therapy 3 Modulation of gene expression by antisense oligonucleotides 4 Ribozymes as therapeutic agents and genetic tools 5 Peptide nucleic acids (PNA) binding-mediated target gene transcription 6 Aptamers for controlling gene expression 7 Enzymes acting on DNA breaks and its relevance in nucleic acid-based therapy 8 Compaction and condensation of DNA 9 Structure, dispersion stability and dynamics of DNA and polycation complexes 10 Structure and structure-activity correlations of cationic lipid/DNA complexes: supramolecular assembly and gene delivery 11 Cellular uptake, metabolic stability and nuclear translocation of nucleic acids 12 Nucleocytoplasmic trafficking 13 Optimizing RNA export for transgene expression 14 Naked plasmid DNA delivery of a therapeutic protein 15 Cationic lipid-based gene delivery 16 Peptide-based gene delivery systems 17 Cationic and non-condensing polymer-based gene delivery 18 Device-mediated gene delivery 19 Basic pharmaeokinetics of oligonucleotides and genes 20 Interstitial transport of macromolecules: implication for nucleic acid delivery in solid tumors 21 Hepatic delivery of nucleic acids using hydrodynamics-based procedure 22 Role of CpG motifs in immunostimulation and gene expression 23 Local cardiovascular gene therapy 24 Gene therapy for cardiovascular disease 25 Gene therapy for the prevention of autoimmune diabetes List of color plates |
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