| Section I Basic Immunology Chapter 1 Overview of the Immune System INNATE IMMUNITY Physical and Chemical Barriers Phagocytic Cells Auxiliary Cells Soluble Mediators Complement Proteins Toll-like Receptors ADAPTIVE IMMUNITY B and T Cells Cytokines Specific Immune Responses Three Phases of Immune Responses Crosstalk between Innate and Adaptive Immunity IMMUNOPATHOLOGY inflammation and Tissue Injury Allergen-induced Immunopathology Autoantigen-induced Immunopathology IMMUNOLOGICAL APPLICATIONS Vaccination Immunotherapys and immunoassays Chapter 2 Cells, Organs and Tissues of the Immune System IMMUNE CELLS Innate Immune Cells Adaptive Immune Cells IMMUNE CELL SURFACE RECEPTORS FOR ANTIGENS Pattern-recognition Receptors on Innate Immune Cells B Cell Receptor on B Cells T Cell Receptor on T Cells MHC Molecules IMMUNE ORGANS AND TISSUES Primary Lymphoid Organs-Bone Marrow and Thymus Secondary Lymphoid Organs and Tissues-Spleen, Lymph Nodes Chapter 3 Soluble Mediators of the Immune System ANTIBODIES Structure of lmmunoglobulins Bifunctional Activities of lmmunoglobulins A Vast Repertoire of Antigen-binding Sites Somatic Hypermutation and Affinity Maturation COMPLEMENT Complement Activation Pathways Complement-mediated Inflammatory Reaction CYTOKINES Chapter 4 The Innate Immune Response COMPONENTS OF INNATE IMMUNITY Physical and Chemical Barriers Phagocytic Cells, NK cells, Blood Proteins and Cytokines and MALT RECOGNITION OF INNATE IMMUNITY Pattern Recognition Receptors and Pathogen-associated Molecular Patterns .. NK Cells Recognition via Their Inhibitory Receptors and Activating Receptors RESPONSE MODELS OF INNATE IMMUNITY Cytotoxicity to Target Cells Killing Microbes and Inflammation Chapter 5 The Adaptive Immune Response ANTIGEN PRESENTATION Types of APCs Antigen Processing Exogenous Peptides Presented by MHC Class II and Endogenous Peptides Presented by MHC Class Co-stimulatory Molecules for T Cell Activation Immunological Synapse Antigen Presentation and the Course of an Immune Response ACTIVATION OF T AND B LYMPHOCYTES B Ceils Responses to TI or TD Antigens Signal Transduction in T and B Cell Activations The Interaction between B Cells and TH Cells : Proliferations and Differentiations of Activated T and B Cells …… |
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