Immunomodulating Drugs for the Treatment of Cancer

This textbook provides a comprehensive resource for clinicians and researchers regarding immunomodulatory (IMiDS) drugs and their rapidly emerging role in cancer medicine. This new class of anticancer agents has made a tremendous impact on the treatment of patients with various malignant diseases, including blood cancers and several cancers of the solid organs. Their popularity in describing is based on several important characteristics including: (1) oral bioavailability, (2)non-chemotherapeutic, (3) extremely well-tolerated in all age groups, (4) ability to activate patient's own immune respomse against cancer, (5) ease of combination with other agents sich as chemotherapy resulting in higher responses as well as (6) variability of anticancer activity. Features: focuses on the scientific/preclinical information published that led to the development of these compounds in cancer medicine; outlines in detail the various clinical trials and current clinical application of these agents in various cancers; addresses the unique toxicity profile that is typically associated with these compounds & touches on the ongoing investigation and future direction of these drugs.