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Primer to the Immune Response: Academic Cell Update Edition

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Primer to the Immune Response: Academic Cell Update Edition

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作 者:Tak W. Mak

出 版 社:

出版时间:2010年11月16日

I S B N:9780123847430

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内容简介

作者简介

Tak W. Mak received his Ph.D. in biochemistry in 1972 from the University of Alberta after completing undergraduate and graduate studies at the University of Wisconsin. In 1997, he was appointed Professor at the University of Toronto. He is also Vice President of Research/Director of the The Campbell Family Institute for Breast Cancer Research. He has co-authored over 350 scientific papers and is a member on numerous advisory boards of scientific journals and medical centers.Mak is best recognized for the discovery of the T-cell receptor in 1984, and is a leader in the development of knockout mice for the analysis of gene function. He has also made significant contributions in the areas of virology, immunology, genetics, molecular signaling, and cancer biology. His laboratory has ongoing efforts to understand the changes in gene function that occur when cells become cancerous, cell signaling pathways, and the role of apoptosis in development and disease.

Mary Evelyn Saunders holds the position of Scientific Editor for the Campbell Family Institute for Breast Cancer Research, Toronto. She completed her B.Sc. degree in Genetics at the University of Guelph, Ontario and received her Ph.D. in Medical Biophysics at the University of Toronto. Dr. Saunders works with Dr. Mak and members of his laboratory on the writing and editing of scientific papers for peer-reviewed journals as well as on various book projects. She takes pride and pleasure in producing concise, clear, highly readable text and making complex scientific processes readily understandable.

作者简介

目录

Preface to the Immunomovie Pt. I Basic Immunology 1

  • Ch. 1 Introduction to the Immune Response
  • Ch. 2 Components of the Immune System
  • Ch. 3 Innate Immunity
  • Ch. 4 The B Cell Receptor: Proteins and Genes
  • Ch. 5 B Cell Development, Activation and Effector Functions
  • Ch. 6 The Major Histocompatibility Complex
  • Ch. 7 Antigen Processing and Presentation
  • Ch. 8 The T Cell Receptor: Proteins and Genes
  • Ch. 9 T Cell Development, Activation and Effector Functions
  • Ch. 10 Regulation of Immune Response in the Periphery
  • Ch. 11 NK, [gamma][delta] T and NKT Cells
  • Ch. 12 Mucosal and Cutaneous Immunity

Pt. II Clinical Immunology

  • Ch. 13 Immunity to Infection
  • Ch. 14 Vaccination
  • Ch. 15 HIV and Acquired Immunodeficiency Syndrome
  • Ch. 16 Tumor Immunology
  • Ch. 17 Transplantation
  • Ch. 18 Immune Hypersensitivity
  • Ch. 19 Autoimmune Diseases
  • Ch. 20 Hemapoietic Cancers

Appendix A Selected Landmark Discoveries in Immunology Appendix B Nobel Prizes Awarded for Work in Immunology Appendix C Comparative Immunology Appendix D Selected CD Markers Appendix E Cytokines, Chemokines and Receptors Appendix F Laboratory Uses of Antibodies Glossary Index

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