Section I: Genetic and molecular mechanisms of neurodegeneration in PD 1 Identifying PD-causing genes and genetic susceptibility factors: current approaches and future prospects Thomas Gasser 2 The impact of genetic research on our understanding of Parkinson's Disease Ted Dawson Ian Martin, Valina L. Dawson 3 Unraveling the role of defective genes Mark Cookson 4 What causes the death of dopaminergic neurons in Parkinson's disease? James Surmeier Jaime N. Guzman, Javier Sanchez-Padilla and Joshua Goldberg 5 Intracellular Signaling Pathways In Dopamine Cell Death And Axonal Degeneration Robert Burke 6 Control of mitochondrial integrity in Parkinson's Disease Serge Przedborski Cristofol Vives-Bauza, Maja Tocilescu, Rosa L. A. deVries, Dana M. Alessi, Vernice Jackson-Lewis 7 Role of Post-Translational Modifications in Modulating the Structure, Function and Toxicity of a-synuclein: Implications for Parkinson's Disease Pathogenesis and Therapies Hilal Lashuel Abid Oueslati, Margot Fournier Section II: Cellular and system-level pathophysiology of the basal ganglia in PD 8 The role of dopamine in modulating the structure and function of striatal circuits James Surmeier Weixing Shen, Michelle Day, Tracy Gertler, Savio Chan, Xianyong Tian and Joshua L. Plotkin 9 Assemblies of glutamate receptor subunits with post-synaptic density proteins and their alterations in Parkinson's disease Monica Di Luca Paolo Calabresi 10 Adenosine-dopamine interactions Micaela Morelli Anna R Carta, Anil Kachroo, Michael A. Schwarzschild 11 Maladaptive plasticity in L-DOPA-induced dyskinesia M. Angela Cenci Christine Konradi 12 Effects of GPi and STN inactivation on physiological, motor, cognitive and motivational processes in animal models of Parkinson's disease Chistelle Baunez Paolo Gubellini 13 Computational physiology of the basal ganglia in Parkinson's disease Hagai Bergman Michal Rivlin-Etzion, Shlomo Elias, Gali Heimer 14 Neurocomputational models of motor and cognitive deficits in Parkinson's Disease Michael J. Frank Thomas V. Wiecki |
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