| A. PROTEINS B. DNA 1. Gene Structure 2. Tools of Molecular Genetics C. MUTATIONS D. CHROMOSOMES 1. Long-Range Gene Relationships and Gene Map 2. Physical Study miques 3. Mitosis 4. Meiosis 5. Mitochondrial DNA 6. Linkage E. PEDIGREE ANALYSIS 1. Symbols 2. Ascertainment B. PRENATAL DIAGNOSIS 1. Ultrasound 2. Amniocentesis 3. Chorionic Villus Sampling 4. Fetal Blood Sampling 5. Maternal Blood Sampling 6. AIpha-Fetoprotein 7. Preimplantatiou Diagnosis for In Vitro Fertilization A. CHANGES IN CHROMOSOME NUMBER B. DOWN SYNDROME 1. Clinical Aspects 2. Genetic Aspects of Down Syndrome 3. Less Common Karyotype Changes in Down Syndrome a. Translocations b. Mosaicism C. SEX CHROMOSOMES 1. X-Chromosome Inactivation 2. XO Females (Turner Syndrome) 3. XXY Males (Klinefelter Syndrome) D. CHROMOSOME STRUCTURE CHANGES 1. Deletions 2. Inversions, Duplications, Insertions 3. Translocations 4. Other Structural Changes E. IMPRINTING …… |
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