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癌症基因治疗学 英文原版

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癌症基因治疗学 英文原版

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作 者:(美)拉蒂姆 著

出 版 社:人民卫生出版社

出版时间:2002-10-1

I S B N:9787117051057

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    内容简介

    .

    作者简介

    目录

    Contributor
    Preface
    PARTⅠ VECTORS FOR GENE THERAPR OF CANCER
    1.Retroviral Vector Design for Cancer Gene Therapy
    2.Noninfections Gene Transfer and Expression Systems for Cancer Gene Therapy
    3.Parvovirus Vectors for the Gene Therapy of Cancer
    4.Antibody-Targeted Gene Therapy
    5.Ribozymes in Cancer Gene Therapy
    6.The Advent of Lentiviral Vectors:Prospects for Cancer Therapy
    PART Ⅱ IMMUNE TARGETIED GENE THERAPY
    7.Immunologic Targets for the Gene Therapy of Cancer
    PART Ⅱa VACCINE STRATEGIES
    8.Development of Eqitope-Specific Immunotherapies for Human Malignancies and Premalignant Lesions Expressing Mutated ras Genes
    PART Ⅱb DENDRITIC CELL-BASED GENE THERAPY
    9.Introduction to Dendritic Cells
    10.DNA and Dendritic Cell-Based Genetic Immunization Against Cancer
    11.RNA-Transfected Dendritic Cells as Immunogens
    PART Ⅱc CYTOKINES AND CO-FACTORS
    12.In Situ Immune Modulation Using Recombinatnt Vaccinia Virus Vectors:Preclinical Studies to Clinical Implementation
    13.The Use of Particle-Mediated Gene Transfer of Immunotherapy of Cance
    PART Ⅱd GENETICALLY MODIFIED EFFECTOR CELLS FOR IMMUNE-BASED IMMUNOTHERAPY
    14.Applications of Gene Transfer in the Adoptive Immunotherapy of Cancer
    15.Update on the Use of Genetically Modified Hematoppietic Stem Cells for Cancer Therapy
    PART Ⅲ ONCOGENE-TARGETED GENE THERAPY
    16.CLINICAL Applications of Tumor-Suppressor Gene Therapy
    17.Cancer Gene Therapy with Tumor Supperssor Genes Involved in Cell-Cycle Control
    18.Cancer Gene Therapy with the p53 Tumor Suppressor Gene
    19.Antisense Downregulation of the Apoptosis-Related Bcl-2and Bcl-xl Proteins:A New Approach to Cancer Therapy
    20.Gene Therpy for Chronic Myelogenous Leukemia
    PART Ⅳ MANULATION OF DRUG RESISTANCE MECHANISMS BY GENE THERARY
    ……
    PART Ⅴ ANTI-ANIOGENESIS AND PRO-APORTOTIC GENE THERAPY
    PART Ⅵ PRODRUG ACTIVATION STRATEGIES FOR GENE THERAPY OF CANCER
    Index

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