| 本书是《Therapeutic Micro/Nano Technology》的影印本，主要讨论了正在兴起的治疗性微米和纳米技术领域。本书所覆盖的主题包括：基于细胞的治疗技术，再生医学——细胞与微米和纳米系统整合(融合)，MEMS与细胞和组织的集成；药物的传递-用于血管内物靶向传递的纳米粒子和非血管系统的药物传递系统(植入性的、口服的、吸入性的)；用于生物界面的分子表面工程，生物分子图案化和细胞图案化。 |
| List of Contributors Foreword Preface I.Cell-based Therapeutics 1.Nano-and Micro-Technology to Spatially and Temporally Control Proteins for Neural Regeneration Anjana Jain and Ravi V Bellamkonda 1.1 Introduction 1.1.1 Response after Injury in CNS and PNS 1.1.2 Nano-and Micro-scale Strategies to Promote Axonal Outgrowth in the CNS and PNS 1.2 Spatially Controlling Proteins 1.2.1 Spatial Control: Permissive Bioactive Hydrogel Scaffolds for Enhanced Regeneration 1.2.2 Spatial Control: Chemical vs.Photochemical Crosslinkers for Immobilization of Bioactive Agents 1.2.3 Other Hydrogel Scaffolds 1.2.4 Spatial Control: Contact.Guidance as a Strategy to Promote Regeneration 1.2.5 Spatial Control: Nerve Guide Conduits Provide an Environment for Axonal Regeneration 1.2.6 Spatial Control: Cell-scaffold Constructs as a Way of Combining Permissive Substrates with Stimuli for Regeneration 1.3 Temporally Controlling the Release of Proteins 1.3.1 Temporal Control: Osmotic Pumps Release Protein to Encourage Axonal Outgrowth 1.3.2 Temporal Control: Slow Release of Trophic Factors Using Microspheres 1.3.3 Temporal Control: Lipid Microtubules for Sustained Release of Stimulatory Trophic Factors 1.3.4 Temporal Control: Demand Driven Release of Trophic Factors 1.4 Conclusion References 2.3-D Fabrication Technology for Tissue Engineering Alice A.Chen, Valerie Liu Tsang, Dirk Albrecht, and Sangeeta N.Bhatia 2.1 Introduction 2.2 Fabrication of Acellular Constructs 2.2.1 Heat-Mediated 3D Fabrication 2.2.2 Light-Mediated Fabrication 2.2.3 Adhesive-Mediated Fabrication 2.2.4 Indirect Fabrication by Molding 2.3 Fabrication of Cellular Constructs 2.4 Fabrication of Hybrid Cell/Scaffold Constructs 2.4.1 Cell-laden Hydrogel Scaffolds by Molding …… |
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