| VOLUME 1 Section I Biology of the Gastrointestinal Tract Chapter I Gastrointestinal Hormones and Neurotransmitters Nigel W. Bunnett John H. Walsh TheChemical Messengers The Receptors Mechanisms of Signal Transduction IntegrativeControl of Gastrointestinal Function Conclusions Chapter 2 Immunology and Inflammation of the Gastrointestinal Tract Martin E Kagnoff GeneralCharacteristics of the Immune System The Intestine as a Lymphoid Organ Immunologic Diseases and Disorders Chapter 3 Principles of Gastrointestinal Neoplasia Anil K. Rustgi Daniel K. Podolsky Mechanisms of NormalCell Proliferation Regulation of NormalCell Proliferation： Signaling Pathways OfCell Growth Responses Characteristics of MalignantCells Mechanisms of Oncogenesis Neoplasia-Associated Genes Biology of Tumor Metastasis Diagnostic Strategies：Current and Future Approaches Principles of Therapy：Current and Future Section H Approach to Patients with Symptoms and Signs Chapter 4 Psychosocial Factors in Gastrointestinal Disorders Douglas A. Drossman AConceptualization Environmental Stress and Gastrointestinal Function Brain-Gut Interactions Psychoneuroimmunology Clinical Relationships Between Psychosocial Factors and Gastrointestinal Illness Clinical Applications Chapter 5 Abdominal Pain， Including the Acute Abdomen Robert E. Glasgow Sean J. Mulvihill Anatomic Basis of Pain Stimulants of Pain Types of Pain An Approach to the Patient with Acute Abdominal Pain An Approach to the Patient withChronic Abdominal Pain Chapter 6 Chronic Functional Abdominal Pain Douglas A. Drossman The Physicians Experience withChronic Function Abdominal Pain Definition， Epidemioiogy， and HealthCare Impact Neurophysiology Clinical Features Clinical Assessment Treatment Approach Chapter 7 Dysphagia， Odynophagia， Heartburn， and Other Esophageal Symptoms Joel E. Richter Dysphagia Odynophagia Heartburn (Pyrosis) Globus Sensation Chest Pain Respiratory; Ear， Nose， and Throat; andCardiac Symptoms Chapter 8 Dyspepsia K. McQuaid Definition Epidemiology Causes of Organic Dyspepsia Functional (Nonulcer) Dyspepsia Evaluation Empirical Treatment Versus Early Endoscopy Treatment of Functional Dyspepsia Chapter 9 Nausea and Vomiting Makau Lee Mark Feldman The Act of Vomiting Neural Pathways and Pathophysiology of Vomiting Clinical Approach to Patients with Nausea and Vomiting Specific Syndromes Associated with Vomiting Consequences of Vomiting Therapy of Vomiting Chapter !0 Diarrhea Kenneth D. Fine Definition of Diarrhea Four Mechanisms of Diarrhea Diagnostic Approach to Patients Some Important Diarrheal Syndromes Chapter 11 Intestinal Gas Alessandra Strocchi Michael D. Levitt Volume andComposition of Bowel Gas Sources of Bowel Gas Clinical Gas Problems Chapter 12 Fecal Incontinence Lawrence R. Schiller Prevalence Mechanisms of Fecal Incontinence Differential Diagnosis of Fecal Incontinence Evaluation of Patients with Fecal Incontinence Treatment Management of Specific Situations Chapter 13 Constipation John E. Lennard-Jones Presenting Symptoms Epidemiology ClinicalClassification Pathophysioiogy Constipation as a Manifestation of Systemic Disorders Constipation as a Manifestation ofCentral Nervous Disease of the Extrinsic Nerve Supply to the Gut Constipation Secondary to Structural Disorders of theColon， Rectum， Anus， and Pelvic Floor Drug Treatment MayCause or Aggravate Constipation Psychological Disorders asCauses or Aggravating Factors inConstipation Clinical Assessment Investigation Medical Treatment ParticularClinical Problems Chapter 14 Acute andChronic Gastrointestinal Bleeding Loren Laine Epidemiology Manner of Presentation Initial Assessment of the Patient Resuscitation Differeritiating Upper from Lower Gastrointestinal Bleeding Diagnostic Evaluation of Patients with Gastrointestinal Bleeding Specific Bleeding Lesions and Their Treatment Chapter 15 Jaundice Steven Lidofsky Bruce E Scharschmidt Determinants of Serum BilirubinConcentration Differential Diagnosis of Jaundice Diagnostic Approach to the Patient with Jaundice Therapeutic Options Section III Nutrition in Gastroenterology Chapter 16 The Malnourished Patient： Nutritional Assessment and Management Samuel Klein Khursheed N. Jeejeebhoy Basic NutritionalConcepts Assessment of Nutritional Status Refeeding the Malnourished Patient Patients with Severe Malabsorption Chapter 17 Enteral and Parenteral Nutrition Samuel Klein C. Richard Fleming Enteral Nutrition Parenteral Nutrition Clinical Applications of Nutrition Support Chapter 18 Obesity， Anorexia Nervosa， and Bulimia Stephen D. Phinney Charles H. Halsted Obesity Anorexia and Bulmia Section IV Topics Involving Multiple Organs Chapter 19 Complications of Gastrointestinal Endoscopy Harvey S. Young Emmet B. Keeffe GeneralComplications Complications of Upper Endoscopy Complications of Sigmoidoscopy andColonoscopy Chapter 20 Diverticula of the Esophagus， Stomach， and Small Bowel William V Harford Zenkers Diverticula Diverticula of the Esophageal Body Esophageal Intramural Pseudodiverticula Gastric Diverticula Duodenal Diverticula Jejunal Diverticula Chapter 21 Hernias and Volvulus of the Gastrointestinal Tract Katherine E. McArthur Diaphragmatic Hernias External Hernias of the Abdominal Wall Groin Hernias (Including Inguinal Hernias) Internal Hernias Gastric Volvulus Midgut Volvulus Volvulus of the Large Bowel Chapter 22 Foreign Bodies and Bezoars K. Hamilton D. Polter Foreign Bodies Bezoars Conclusions Chapter 23 Caustic Injury to the Upper Gastrointestinal Tract Peter M. Loeb Abram M. Eisenstein Caustic Agents Pathogenesis and Pathology Clinical Features Diagnostic Studies Treatment Recommended Approach LateComplications Button Battery Ingestion Chapter 24 Nonsteroidal Anti-Inflammatory Drugs and Gastrointestinal Disease ByronCryer Introduction Epidemioiogy Mechanisms of Toxicity of NSAIDs Clinical Manifestations of NSAID Injury Throughout the Gastrointestinal Tract Therapeutic Effects of NSAIDs in the Large Intestine Chapter 25 Abdominal Abscesses and Gastrointestinal Fistulas J. P. Minei J.Champine Abdominal Abscesses Gastrointestinal Fistulas Chapter 26 Protein.Losing Gastroenteropathy Thomas A. Brasitus Bruce M. Bissonnette Definition and History Etiology Diagnosis Treatment Chapter 27 GastrointestinalComplications of Solid Organ and Bone Marrow Transplantation Sally A. S. Weisdorf William D. Payne Side Effects of Immunosuppressive Agents InfectiousComplications NutritionalComplications MalignantComplications Solid Organ Transplantation Bone Marrow Transplantation Graft-Versus-Host Disease Chapter 28 Gastrointestinal Manifestations of the Acquired Immunodeficiency Syndrome C. Mel Wilcox Scott L， Friedman Evaluation and Management of Gastrointestinal and Hepatobiliary Symptoms in AIDS Diarrhea Weight Loss Odynophagia and Dysphagia Abdominal Pain Anorectal Disease Jaundice and Hepatomegaly Gastrointestinal Bleeding Chapter 29 Effects on the Gut of Systemic Disease and Other ExtraintestinalConditions John R. Weber JamesC. Ryan Endocrine Disease Pregnancy Chapter 31 Anatomy and Developmental and Acquired Anomalies of the Esophagus John D. Long RoyC. Orlando Anatomy Embryology Developmental Anomalies Acquired Anomalies Chapter 32 Motor Physiology and Motor Disorders of the Esophagus Ray E.Clouse N. E. Diamant Overview of Normal Function Innervation Coordinated Esophageal Motor Activity Mechanisms Producing Disordered Motility Neoplastic Diseases Hematologic Diseases Rheumatologic andCollagen Diseases Renal Disease Neurologic Disease Pulmonary Disease Cardiac Disease Infiltrative Diseases Disorders of Lipid Metabolism Chapter 30 Oral andCutaneous Manifestations of Gastrointestinal Disease Ginat W. Mirowski 17mothy G. Berger Mouth and Tongue MucocutaneousCandidiasis Mucocutaneous Features of HIV Infection Mucocutaneous Ulcerative Diseases Vesiculobullous Diseases Cutaneous Manifestations of Intestinal Disease， Including Inflammatory Bowel Disease Vascular andConnective Tissue Disorders Cutaneous Markers Associated with Gastrointestinal Malignancies Malabsorption/Deficiency Syndromes Vitamin Deficiencies Pancreatic Disease and the Skin Cutaneous Manifestations of Liver Disease Parasitic Diseases of the Gut and Skin Section V Esophagus Diagnosing Motor Disorders Disorders of the UES andCervical Esophageal Region Achalasia Other Hypermotility Disorders of the Distal Esophagus Disorders Restricted to the LES Systemic Diseases Associated with Esophageal Hypomotility Chapter 33 Gastroesophageal Reflux Disease and Its Complications Peter J. Kahrilas Definitions and Epidemiology Histopathology of Esophagitis Pathogenesis Clinical Presentation and Natural History Management …… VOLUME 2 index |
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