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计算生命科学/会议录Computational Life Sciences

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计算生命科学/会议录Computational Life Sciences

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作 者:Michael R. Berthold 著

出 版 社:Oversea Publishing House

出版时间:2005-10-1

I S B N:9783540291046

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内容简介

This book constitutes the refereed proceedings of the First International Symposium on Computational Life Sciences, CompLife 2005, held in Konstanz, Germany in September 2005. The 21 revised full papers presented together with 3 papers of a workshop on Distributed Data Mining in the Life Sciences (LifeDDM) were carefully reviewed and selected from 49 initial submissions. The papers cover areas ranging from high-level system biology to data analysis related to mass spec traces and are organized in topical sections on systems biology, data analysis and integration, structural biology, genomics, computational proteomics, molecular informatics, molecular structure determination and simulation, and distributed data mining.

作者简介

目录

Systems Biology
 Structural Protein Interactions Predict Kinase-Inhibitor Interactions in Upregulated Pancreas Tumour Genes Expression Data
 Biochemical Pathway Analysis via Signature Mining
 Recurrent Neuro-fuzzy Network Models for Reverse Engineering Gene Regulatory Interactions
Data Analysis and Integration
 Some Applications of Dummy Point Scatterers for Phasing in Macromolecular X-Ray Crystallography
 BioRegistry: A Structured Metadata Repository for Bioinformatic Databases
 Robust Perron Cluster Analysis for Various Applications in Computational Life Science
Structural Biology
 Multiple Alignment of Protein Structures in Three Dimensions
 Protein Annotation by Secondary Structure Based Alignments (PASSTA)
 MAPPIS: Multiple 3D Alignment of Protein-Protein Interfaces
Genomics
 Frequent Itemsets for Genomic Profiling
 Gene Selection Through Sensitivity Analysis of Support Vector Machines
 Tile Breakpoint Graph in Ciliates
Computational Proteomics
 ProSpect: An R Package for Analyzing SELDI Measurements Identifying Protein Biomarkers
 Algorithms for the Automated Absolute Quantification of Diagnostic Markers in Complex Proteomics Samples
 Detection of Protein Assemblies in Crystals
Molecular Informatics
 Molecular Similarity Searching Using COSMO Screening Charges (COSMO/3PP)
 Increasing Diversity in In-silico Screening with Target Flexibility
……
Molecular Structure Determination and Simulation
Distributed Data Mining
Author Index

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