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Foye医药学原理Foye's Principles of Medicinal Chemistry

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Foye医药学原理Foye's Principles of Medicinal Chemistry

最 低 价:¥200.40

定 价:¥916.00

作 者:David A Williams 著

出 版 社:Oversea Publishing House

出版时间:2002-2-1

I S B N:9780683307375

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内容简介

This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.
Massachusetts College of Pharmacy and Health Sciences, Boston. Textbook, for pharmacy students, now includes an overview of the drug development process from the perspective of an industrial research scientist. Also new to this edition: an overview of drug receptors, case studies, selected readings, and a companion web page. Previous edition: c1995.

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目录

Introduction Origins of Medicinal Chemistry
Part Ⅰ Principles of Drug Discovery
 Overview Drug Design and Development: A Perspective
 1. Natural Products
  2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity
 3. Molecular Modeling and Drug Design
  4. Receptors and Drug Action
 5. Drug Design Through Enzyme Inhibition
  6. Peptide and Protein Drugs
 7. Physicochemical and Biopharmacemical Properties of Drug Substances and Pharmacokinetics
  8. Drug Metabolism
 9. U.S. Drug Regulation: An Overview
Part Ⅱ Pharmacodynamic Agents
Overview Drug Receptors: A Perspective
 Section 1 Drugs Affecting Neurotransmission
  10. Drugs Affecting Cholinergic Neurotransmission
  11. Drugs Affecting Adrenergic Neurotransmission
  12. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission
  13. Local Anesthetics
 Section 2 Drugs Affecting Central Nervous System
  14. Volatile Anesthetics
  15. Hypnotics
  16. Antiseizure Drugs
  17. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents
  18. Hallucinogens, Stimulants, and Related Drugs of Abuse
  19. Opioid Analgesics
  20. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents
 Section 3 Drugs Affecting the Cardiovascular System
  21. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs
  22. Diuretics
  23. Angiotensin Converting Enzyme Inhibitors, Antagonists and Calcium Blockers
  24. Central and Peripheral Sympatholytics and Vasodilators
……
Part Ⅲ Recent Advances in Drug Discovery
Appendices pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases pH Values for Tissue Fluids

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