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| Preface Acknowledgements Part Ⅰ Developmental biology 1 Basic biology 2 The cell 3 The chromosomes 4 DNAstructure 5 DNAreplication 6 RNAstructure 7 Production of messenger RNA 8 Protein synthesis 9 The cell cycle 10 Gametogenesis 11 Embryology 12 Sexual differentiation Part Ⅱ Medical genetics 13 The place of genetics in medicine 14 Chromosomal aneuploidies 15 Chromosome structural abnormalities 16 Mendel's laws 17 Autosomal dominant inheritance 18 Autosomalrecessiveinheritance 19 Intermediate inheritance 20 Sex-related inheritance 21 Congenital abnormalities 22 Multifactorial threshold traits 23 The common disorders of adult life 24 Twin studies 25 Normal polymorphism 26 Allele frequency 27 Genetic linkage and disease association 28 Gene mapping 29 Mutagenesis and DNA repair 30 Mutations 31 The molecular biology of cancer 32 Familial cancers 33 lmmunogenetics Part Ⅲ Clinical applications of genetics 34 Clinical applications of genetics: an overview 35 Pedigree drawing 36 Risk assessment 37 Dysmorphology 38 Chromosome analysis 39 Biochemical diagnosis 40 Reproductive genetic counselling 41 Prenatal sampling 42 Linkage analysis 43 DNA sequencing 44 Southern blotting 45 The polymerase chain reaction 46 DNAprofiling 47 Avoidance and prevention of disease 48 The management of genetic disease Glossary Appendix: Information resources Index |
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