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作 者:Bernhard O. Palsson 著 著
出 版 社:Oversea Publishing House
出版时间:2006-1-1
I S B N:9780521859035
| Bernhard O.Palsson, Professor of Bioengineering and Adjunct Professor of Medicine, University of California, San Diego. |
| Preface 1 Introduction 2 Basic Concepts in Systems Biology PART I.RECONSTRUCTION OF BIOCHEMICAL NETWORKS 3 Metabolic Networks 4 Transcriptional Regulatory Networks PART II.MATHEMATICAL REPRESENTATION OF RECONSTRUCTED NETWORKS 5 Signaling Networks 6 Basic Features of the Stoichiometric Matrix 7 Topological Properties 8 Fundamental Subspaces of S 9 The (Right) Null Space of S 10 The Left Null Space of S 11 The Row and Column Spaces of S PART III CAPABILITIES OF RECONSTRUCTED NETORKS 12 Dual Causality 13 Properties of Solution Spaces 14 Sampling Solution Spaces 15 Finding Functional States 16 Parametric Sensitivity 17 Epilogue APPENDIX A.Nomenclature and Abbreviations APPENDIX B.E.coli Core Metabolic Network Bibliography Index |
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