And men should know that from nothing else but from the brain come joys, laughter and jests, and sorrows, griefs, de- spondency and lamentations. And by this, in an especial manner, we acquire wisdom and knowledge, and see and hear and know what are [oul and what are [air, what sweet and what unsavory . . . and by the same organ we become mad and delirious and [ears and terrors assail us, some by day, and dreams and untimely wanderings, and cares that are not suitable and ignorance o[ present circumstances, dis- quietude and unskillfulness. All these things we endure from the brain, when it is not healthy, but is more cold, more mois~ or more dry than natural, or when it suffers other preternatural and unusual affliction. Hippocrates, fifth century B.c
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